Research may lead to new insights on the genetics of height

Credit: Pixabay/CC0 Public Domain

A study published in the Journal of Bone and Mineral Research points to genes and gene pathways that are strong candidates to influence the genetic regulation of human height.

The study examined data from genome-wide association studies of human height, which have identified numerous height-associated regions in the , and assessed the expression of these genetic regions in different layers of the growth plate, or areas of new bone growth during childhood.

"Our results point to expressed in earlier stages of chondrocyte differentiation as most influencing human height," Nora Renthal, MD, Ph.D., of Boston Children's Hospital and Harvard Medical School.

Explore further

New approach to understanding bone strength pays dividends for osteoporosis

More information: Nora E. Renthal et al, Genes with specificity for expression in the round cell layer of the growth plate are enriched in genomewide association study ( GWAS) of human height, Journal of Bone and Mineral Research (2021). DOI: 10.1002/jbmr.4408
Provided by Wiley
Citation: Research may lead to new insights on the genetics of height (2021, August 4) retrieved 27 November 2021 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors