AI can be used to identify benign thyroid nodules and reduce unnecessary biopsies

Credit: Pixabay/CC0 Public Domain

Artificial intelligence (AI) can be used to identify thyroid nodules seen on thyroid ultrasound that are very unlikely to be cancerous, reducing a large number of unnecessary biopsies, according to a new study being presented Saturday at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

Thyroid nodules are very common. Fine needle aspiration biopsy is used to diagnose . However most biopsies produce benign (noncancerous) results and are potentially avoidable, according to study lead researcher Nikita Pozdeyev, M.D., Ph.D., of the University of Colorado Anschutz Medical Campus in Aurora, Colo.

In the new study, researchers used machine learning, a type of AI, to analyze ultrasound images of . Machine learning is the process of using mathematical models of data to help a computer learn without direct instruction.

More than 30,000 images from 621 thyroid nodules were used to train the model that classifies thyroid nodules as "cancer" or "no cancer." The model was tested on a different set of 145 nodules collected at another healthcare system.

The AI-based model achieved a sensitivity (ability to not miss cancer) of 97%, and a specificity (ability to correctly identify a cancer) of 61%. "This study demonstrates that the ultrasound-based AI classifier of thyroid nodules achieves sensitivity comparable to that of thyroid biopsy with ," Pozdeyev said.

"We believe this is a good next step to improving and avoiding unnecessary procedures," he said. He noted that prospective clinical trials are needed before this tool can be accepted as a standard of care.

"We demonstrated that using AI analysis of ultrasound images to rule out thyroid cancer and avoid biopsy is definitely possible," he said. "This technology could assist radiologists and endocrinologists in choosing which thyroid nodules should undergo biopsy, especially those in the community who may not review a large number of thyroid ultrasound images."

More information: Pozdeyev will present at the Society's ENDO 2022 thyroid health news conference at 11:30 AM Eastern on Monday, June 13.

Citation: AI can be used to identify benign thyroid nodules and reduce unnecessary biopsies (2022, June 11) retrieved 29 November 2023 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Thyroid cancer now diagnosed with AI photoacoustic/ultrasound imaging


Feedback to editors