This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:

fact-checked

peer-reviewed publication

reputable news agency

proofread

Updated guidance provided for GI clinicians on alpha-gal syndrome

Updated guidance provided for GI clinicians on alpha-gal syndrome

A subset of patients with alpha-gal allergy have gastrointestinal symptoms without skin changes or anaphylaxis, according to a clinical practice update published in the April issue of Clinical Gastroenterology and Hepatology.

Sarah K. McGill, M.D., from the University of North Carolina at Chapel Hill, and colleagues provide information relating to the presentation and management of alpha-gal syndrome in order to increase awareness among gastroenterologists.

The authors note that a subset of alpha-gal allergic patients show , such as , diarrhea, nausea, or vomiting, without skin changes or anaphylaxis. Among patients with gastrointestinal distress and increased serum alpha-gal immunoglobulin E (IgE) antibodies whose symptoms are relieved adequately on an alpha-gal avoidance diet, which eliminates pork, beef, and mammalian-derived products, alpha-gal syndrome can be diagnosed. Counseling for an alpha-gal avoidance diet is suggested for patients with suspected alpha-gal allergy because it is the primary management. Measures to avoid should also be included in counseling, because additional bites can cause a further increase in alpha-gal IgE titers and worsen the allergy. Referral to allergists is recommended for who also have reactions such as facial swelling, urticaria, and respiratory difficulty.

"It is important for gastroenterologists to be aware of this condition and to be capable of diagnosing and treating it in a timely manner," the authors write.

Two authors disclosed financial ties to the medical technology industry.

More information: Sarah K. McGill et al, AGA Clinical Practice Update on Alpha-Gal Syndrome for the GI Clinician: Commentary, Clinical Gastroenterology and Hepatology (2023). DOI: 10.1016/j.cgh.2022.12.035

Copyright © 2023 HealthDay. All rights reserved.

Citation: Updated guidance provided for GI clinicians on alpha-gal syndrome (2023, April 4) retrieved 15 June 2024 from https://medicalxpress.com/news/2023-04-guidance-gi-clinicians-alpha-gal-syndrome.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Lone star tick bites may be to blame for unexplained digestive problems

13 shares

Feedback to editors