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Parkinson's & Movement disorders news
Genetics
Therapeutic target identified to neutralize toxic forms of Parkinson's-associated protein
Researchers from the UAB have identified a region in the early aggregates of the alpha-synuclein protein that can be targeted to prevent its conversion into the toxic amyloid fibrils that accumulate in the brains of people ...
3 hours ago
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Medications
Leprosy drug may be effective in Huntington's disease, study suggests
A preclinical study from Karolinska Institutet offers hope for treating severe neurodegenerative diseases with an existing drug. The study suggests that the leprosy drug clofazimine may be effective in the treatment of Huntington's ...
May 3, 2024
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Epigenomic analysis sheds light on risk factors for amyotrophic lateral sclerosis
For most patients, it's unknown exactly what causes amyotrophic lateral sclerosis (ALS), a disease characterized by degeneration of motor neurons that impairs muscle control and eventually leads to death.
May 2, 2024
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Web platform and app aim to improve quality of life for people with Parkinson's disease
Parkinson's disease is one of the most prevalent neurodegenerative conditions worldwide. It causes motor impairments such as tremors, slow movement, muscle stiffness, and balance problems. Memory can also worsen as the disease ...
May 2, 2024
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Researchers target neurogenesis in new approach to treat Parkinson's disease
Researchers at the University of Toronto have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and few effective ...
Apr 30, 2024
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Study shows social connection is key for youth suicide prevention efforts
Social connectedness, a feeling of belonging at school and in the community, can play an important role in suicide prevention among high-risk teens, new research from the University of Oregon finds.
Apr 30, 2024
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Scientists discover potential biomarkers of environmental exposures in Parkinson's disease
A team of Northwestern Medicine investigators has discovered novel DNA methylation patterns in the blood of patients with Parkinson's disease, according to findings published in Annals of Neurology.
Apr 26, 2024
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Recognizing symptoms of Parkinson's disease
April is Parkinson's Disease Awareness Month, which make this a good time to learn about the symptoms of Parkinson's disease.
Apr 26, 2024
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Genetic variations may predispose people to Parkinson's disease following long-term pesticide exposure, study finds
A new UCLA Health study has found that certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson's disease.
Apr 25, 2024
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Differentiating cerebral cortical neurons to decipher molecular mechanisms of neurodegeneration
A research team led by Professor Haruhisa Inoue (Department of Cell Growth and Differentiation) derived iPS cells (iPSC) from α-synucleinopathy patients with early-onset familial Parkinson's disease (PD) carrying the α-synuclein ...
Apr 25, 2024
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Longest study to date assesses cognitive impairment over time in adults with essential tremor
Essential tremor, a nervous system disorder that causes rhythmic shaking, is one of the most common movement disorders. A new study published in the Annals of Neurology reveals details on the increased risk of mild cognitive ...
Apr 24, 2024
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Improving prospects for people with Parkinson's
In an evolving journey toward understanding and supporting those living with Parkinson's disease, a new report offers fresh insights into the burden it places on those affected.
Apr 22, 2024
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Analyzing the progression in retinal thickness could predict cognitive progression in Parkinson's patients
Although there are still some aspects pending confirmation for its use in the clinical setting, and its resolution needs to be improved slightly, a study by the UPV/EHU and Biobizkaia has shown that a method routinely used ...
Apr 19, 2024
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Battle against fatal neurodegenerative disease advances on two fronts
European researchers are pioneering a vaccine and treatment for amyotrophic lateral sclerosis.
Apr 19, 2024
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AI speeds up drug design for Parkinson's by ten-fold
Researchers have used artificial intelligence techniques to massively accelerate the search for Parkinson's disease treatments.
Apr 17, 2024
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New drug may slow rapid progression of Parkinson's disease
Prasinezumab, a monoclonal antibody, is shown to reduce signs of motor deterioration in individuals with Parkinson's disease (PD) who have rapidly progressing disease, as reported in an exploratory analysis of data from a ...
Apr 16, 2024
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Scientists identify cell vulnerability 'fingerprint' related to Parkinson's, Lewy body dementia
A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.
Apr 16, 2024
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Researchers identify brain region involved in control of attention
Researchers at the University of Iowa in a new study have linked a region in the brain to how humans redirect thoughts and attention when distracted. The connection is important because it offers insights into cognitive and ...
Apr 15, 2024
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Real-world data fill knowledge gap to assess treatment options for infants with spinal muscular atrophy
Findings from a recent study in the Journal of Neuromuscular Diseases demonstrate the effectiveness of disease-modifying treatments (DMTs) in infants with spinal muscular atrophy (SMA). The study's results add further support ...
Apr 15, 2024
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Stirring up emotions: Parkinson's disease alters emotion-related bodily sensations, finds study
Researchers at the University of Turku and Turku University Hospital in Finland have shown that bodily sensations related to emotions are altered by the neurological disorder Parkinson's disease.
Apr 15, 2024
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