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Parkinson's & Movement disorders news

Parkinson's & Movement disorders

What the trained eye cannot see: Detecting movement defects in early stage Parkinson's disease

A technique that uses videos and machine learning to quantify motor symptoms in early-stage Parkinson's disease could help reveal signs of the disease and other movement disorders earlier, which could lead to better treatment ...

Genetics

Researchers discover rare sequence variants that associate with a high risk of Parkinson's disease

Scientists at deCODE genetics, a subsidiary of AMGEN, have discovered rare sequence variants, predicted to cause a loss of function of ITSN1, that are associated with a high risk of Parkinson's disease. The findings also ...

Parkinson's & Movement disorders

Fecal microbiota transplant no aid for Parkinson's disease

Fecal microbiota transplantation (FMT) is safe but does not offer clinically meaningful improvements for Parkinson's disease (PD), according to a study published online July 29 in JAMA Neurology.

Health

What your gait says about your health

Walking requires a huge number of signals between your brain and the muscles in your arms, chest, back, abdomen, pelvis and legs. Something that looks relatively straightforward is in fact incredibly complex. And the pace ...

Neuroscience

Gut protein may protect brain cells in Parkinson's disease

Nearly 10 million people worldwide suffer from Parkinson's disease (PD), a condition causing muscle rigidity and tremors due to the loss of the chemical dopamine in the brain. One cause of PD is exposure to toxins. In a recent ...

Parkinson's & Movement disorders

Machine learning helps define new subtypes of Parkinson's disease

Researchers at Weill Cornell Medicine have used machine learning to define three subtypes of Parkinson's disease based on the pace at which the disease progresses. In addition to having the potential to become an important ...

Medical research

Diabetic drug could slow the progression of Parkinson's disease

A hallmark of Parkinson's disease is the degeneration of a group of dopaminergic neurons in the brain, which play key roles in movement initiation and co-ordination. When these neurons degenerate it leads to akinesia (lack ...

Parkinson's & Movement disorders

Eye exam could lead to early Parkinson's disease diagnosis

A simple eye exam combined with powerful artificial intelligence (AI) machine learning technology could provide early detection of Parkinson's disease, according to research being presented at the annual meeting of the Radiological ...

Parkinson's & Movement disorders

Emotion detection in Parkinson's disease

Parkinson's disease is a neurodegenerative disorder that leads to significant disturbances to motor control resulting in involuntary tremor, shuffling gait, muscular rigidity, and other problems. The disease also leads to ...

Parkinson's & Movement disorders

Mimicking brain cells to understand Parkinson's

A device that mimics the brain cells affected by Parkinson's disease could help find new treatments for the condition. The device is described in the Elsevier journal Organs-on-a-Chip. "We have created human neurons that ...

Neuroscience

Leap forward for brain research

Pre-clinical research into deadly brain cancer, Parkinson's, dementia, epilepsy and other major psychiatric and neurological conditions can speed up with the global commercialisation of an advanced neuromedium, called BrainPhys.

Parkinson's & Movement disorders

Common diabetes drugs may prevent Parkinson's

Elevated risk of Parkinson's disease among people with type 2 diabetes appears to be reduced by some medications used to treat their diabetes, finds a new study led by UCL researchers.

Parkinson's & Movement disorders

Gut bacteria could be responsible for side effect of Parkinson's drug

Bacteria in the small intestine can deaminate levodopa, the main drug that is used to treat Parkinson's disease. Bacterial processing of the unabsorbed fractions of the drug results in a metabolite that reduces gut motility. ...