Medical research
Amyloid formation: Designer proteins light the way forward
Insight into the mechanism of protein aggregation provides a model system that could lead to treatments for several associated diseases
Jul 17, 2013
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Page 12 - Agency for Science, Technology and Research (A*STAR), Singapore
Genetics
Team develops method to better identify genes involved in diseases
Scientists at A*STAR's Genome Institute of Singapore (GIS) have developed a new technique that simplifies the task of identifying the precise DNA mutations that cause disease, which lays the groundwork for the development ...
Apr 6, 2015
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Medical research
Smooth muscle cells designed to mimic blood vessels in the brain may help to understand Alzheimer's
A technique to grow cells very similar to smooth muscle cells found in brain arteries, will make it easier to study the contribution of blood vessel disease to neurodegenerative conditions, a new study shows.
Dec 17, 2014
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Immunology
Patient, heal thyself: Solution to personalised treatment for chronic infections could lie in patient's own blood
A recent discovery by scientists at A*STAR's Singapore Institute for Clinical Sciences (SICS), in close collaboration with researchers at the Singapore Immunology Network (SIgN), provides hope for a new personalised treatment ...
Sep 20, 2013
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Oncology & Cancer
Unlocking a key to kidney cancer: Study advances understanding of tumor growth
Researchers from A*STAR's Institute of Molecular and Cell Biology (IMCB) and National Cancer Centre Singapore (NCCS) have discovered how the loss of a gene, PBRM1, can lead to the development of kidney cancer. The work is ...
Jul 28, 2023
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Oncology & Cancer
Technique to generate antibodies for natural immune responses to cancer and leukemia
The artificial enhancement of the body's natural immune defenses is a potential weapon in the battle against diseases such as leukemia. A*STAR researchers are honing methods to boost the interactions between antibodies and ...
Mar 23, 2016
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Diseases, Conditions, Syndromes
Hepatitis B exposure trains newborns' immune cells, enhancing their ability to respond to pathogens
Exposure to Hepatitis B virus (HBV) in utero can help 'mature' a human neonatal immune system and may improve the capacity of human neonatal immune cells to respond to secondary infections, an international research team ...
Nov 4, 2015
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Psychology & Psychiatry
Children born to mothers with diabetes during pregnancy are at risk of developing attention problems
Babies born to mothers who develop diabetes during pregnancy – known as gestational diabetes (GDM) – are shown to have attentional deficiencies as early as 6–18 months of age, suggesting the need to reduce insulin resistance ...
Jul 12, 2017
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Medical research
Understanding and improving the body's fight against pathogens
Scientists from A*STAR's Bioprocessing Technology Institute (BTI) have uncovered the crucial role of two signalling molecules, DOK3 and SHP1, in the development and production of plasma cells. These discoveries, published ...
Sep 1, 2014
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Diseases, Conditions, Syndromes
Human genomic pathways to bronchitis virus therapy
Viral replication and spread throughout a host organism employs many proteins, but the process is not very well understood. Scientists at A*STAR have led a collaborative study to learn which host factors play a key role in ...
Nov 18, 2015
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