Buck Institute for Age Research

The Buck Institute for Research on Aging is the United States' first independent biomedical research institute devoted solely to research on aging and age-related disease. The mission of the Buck Institute is to extend the healthspan, the healthy years of life. The Institute, a nonprofit organization located in Novato, California, began its research program in 1999. It is named for Marin County philanthropists Leonard and Beryl Buck, whose estate funded the generous endowment that helped establish the Institute, and the Buck Trust currently contributes approximately $6 million annually to support the Institute's work. In May 2007, the Institute established a cooperative agreement with the University of California's Davis and Merced campuses to coordinate stem-cell research, a move hailed by UC as a collaboration that "strengthens California's leadership in stem cell research and moves it forward in an efficient, safe and cost-effective manner." The Institute was designed by architect I.M. Pei who submitted an unsolicited proposal to design the research facility.


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Medical research

New paradigm for treating 'inflammaging' and cancer

Intermittent dosing with rapamycin selectively breaks the cascade of inflammatory events that follow cellular senescence, a phenomena in which cells cease to divide in response to DNA damaging agents, including many chemotherapies. ...


Serotonin receptor is involved in eczema and other itch conditions

Dermatologists have long known that available treatments for chronic itch, including eczema, are simply not up to scratch. But scientists have now discovered a new gene that promotes itch, suggesting a way forward for powerful ...

Parkinson's & Movement disorders

Mitochondria are altered in human cell model of Parkinson's disease

Based on research in fruit flies, it has long been suspected that the most common mutation linked to both sporadic and familial Parkinson's disease (PD) wreaks its havoc by altering the function of mitochondria in neurons ...

Medical research

Senescent cells play an essential role in wound healing

Senescent cells have a bad-guy reputation when it comes to aging. While cellular senescence - a process whereby cells permanently lose the ability to divide when they are stressed - suppresses cancer by halting the growth ...

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