Cold Spring Harbor Laboratory

Neuroscience

Mapping the path from smell to perception

Our sense of smell has a powerful effect on our behavior and emotions. Aromas can evoke vivid memories of the past or warn us of a smoldering fire. Yet to neuroscientists, smell remains the most mysterious of our five senses.

Neuroscience

Got junk food on the brain? These cells may be to blame

A region of the brain called the amygdala is responsible for powerful emotions like fear. Now, researchers have found the amygdala may also be to blame for overeating. Cold Spring Harbor Laboratory (CSHL) Professor Bo Li ...

Neuroscience

Sniffing out the brain's smelling power

Since their discovery over 100 years ago, neurons called tufted cells, in the brain's olfactory bulb, have been difficult to study. The close proximity between tufted cells and other neurons called mitral cells has restricted ...

Medical research

The unexpected cells helping to shape young brains

When the brain first wires itself up in early development, it creates more connections than it actually needs. Some of these connections, or synapses, will transmit critical signals as young animals begin to sense their surroundings. ...

Medical research

Disarming the immune system's lethal lung response

Neutrophils, the most abundant type of white blood cell, are the body's first line of defense against infection. Foreign pathogens can stress the body and activate neutrophils. When activated, neutrophils employ various weapons ...

Genetics

Exposing the evolutionary weak spots of the human genome

Mutations can be good and bad. Sometimes they help an organism adapt and survive. Other times they are so harmful that an organism can't survive or reproduce. Cold Spring Harbor Laboratory (CSHL) Professor Adam Siepel's team ...

Immunology

How the thymus trains T cells to fight infections

T cells are a special class of white blood cells that patrol the body and attack infected or foreign tissue. They learn to distinguish friendly proteins from dangerous ones in an organ called the thymus. However, when T cells ...

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