German Center for Neurodegenerative Diseases

Genetics

Risk gene for Alzheimer's has early effects on the brain

A genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with certain memory tasks. Researchers from the German Center for Neurodegenerative Diseases (DZNE) and the Ruhr-Universität ...

Medical research

Lumpy proteins stiffen blood vessels of the brain

Deposits of a protein called 'Medin,' which manifest in virtually all older adults, reduce the elasticity of blood vessels during aging and hence may be a risk factor for vascular dementia. Experts from the German Center ...

Diseases, Conditions, Syndromes

'Hotspots' of a SARS-CoV-2 infection in the human body

An infection with the coronavirus SARS-CoV-2 can affect multiple organs. With this in mind, researchers of the German Center for Neurodegenerative Diseases (DZNE) and Cornell University in the US have investigated cellular ...

Neuroscience

A tailor-made molecule that ties nerve connections

Researchers from the German Center for Neurodegenerative Diseases (DZNE), UK and Japan have developed a neurologically acting protein and tested it in laboratory studies. In mice, the experimental compound ameliorated symptoms ...

Neuroscience

A 'feeling' for dementia?

A research team led by the German Center for Neurodegenerative Diseases (DZNE) concludes that personal perception can be an important indicator for the early detection of Alzheimer's disease. In a new study involving 449 ...

Neuroscience

Noise disturbs the brain's compass

Our sense of direction tends to decline with age. In the scientific journal Nature Communications, researchers from the German Center for Neurodegenerative Diseases (DZNE) and experts from the U.S. report on new insights ...

Neuroscience

Alzheimer research: Noise-inducing neurons shut down memories

Neurons that are responsible for new experiences interfere with the signals of neurons that contain memories and thereby disturb the recall of memories—at least in mice. The research group of Martin Fuhrmann of the German ...

Alzheimer's disease & dementia

Mouse study suggests immune cells could protect against Alzheimer's

Scientists at the German Center for Neurodegenerative Diseases (DZNE), the Ludwig-Maximilians-Universitaet (LMU) Munich and Denali Therapeutics (South San Francisco, CA, U.S.) have developed an approach to stimulate immune ...

Neuroscience

A good blood supply is good for memory

Memory performance and other cognitive abilities benefit from a good blood supply to the brain. This applies in particular to people affected by a condition known as "sporadic cerebral small vessel disease." Researchers of ...

Oncology & Cancer

Artificial intelligence tracks down leukemia

Artificial intelligence can detect one of the most common forms of blood cancer—acute myeloid leukemia (AML)—with high reliability. Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the University ...

page 2 from 4