The German Center for Neurodegenerative Diseases (German: Deutsches Zentrum für Neurodegenerative Erkrankungen, DZNE) aims to develop new preventive and therapeutic approaches for neurodegenerative diseases. To accomplish this the DZNE follows a translational approach. This means that fundamental research is closely related to clinical research, population studies and health care research. In total there are nine sites all over Germany: Berlin, Bonn, Dresden, Göttingen, Magdeburg, Munich, Rostock / Greifswald, Tübingen and Witten. At each site the DZNE works closely with universities, university hospitals and other partners. The DZNE receives 90 percent of its funding from the Federal Ministry of Education and Research and 10 percent from the respective federal states containing DZNE sites.
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Long before the onset of dementia, there is evidence for increased activity of the brain's immune system. Researchers from DZNE and the University Hospital Bonn (UKB) come to this conclusion based on a study of more than ...
Jan 12, 2022
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Subjective memory disorders in conjunction with conspicuous levels of beta-amyloid proteins in the cerebrospinal fluid are a strong indication of developing Alzheimer's disease. This is the conclusion of a DZNE study involving ...
May 12, 2022
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Our sense of direction tends to decline with age. In the scientific journal Nature Communications, researchers from the German Center for Neurodegenerative Diseases (DZNE) and experts from the U.S. report on new insights ...
Jun 11, 2020
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At the beginning of neurodegenerative disease, the immune cells of the brain—the "microglia"—take up glucose, a sugar molecule, to a much greater extent than hitherto assumed. Studies by the DZNE, the LMU München and ...
Oct 13, 2021
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The coronavirus SARS-CoV-2 is known to infect cells via the receptor ACE2. An international research team under German-Finnish coordination has now identified neuropilin-1 as a factor that can facilitate SARS-CoV-2 entry ...
Oct 20, 2020
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According to a study published in the journal Nature by scientists of the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, inflammatory mechanisms caused by the brain's immune system drive the ...
Dec 21, 2017
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Researchers at the DZNE and the University Medical Center Göttingen (UMG) have identified molecules in the blood that can indicate impending dementia. Their findings, which are presented in the scientific journal EMBO Molecular ...
Oct 11, 2021
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Scientists at the German Center for Neurodegenerative Diseases (DZNE) have identified a group of proteins that help to regenerate damaged nerve cells. Their findings are reported in the journal Neuron.
Aug 7, 2019
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Researchers from the German Center for Neurodegenerative Diseases (DZNE), UK and Japan have developed a neurologically acting protein and tested it in laboratory studies. In mice, the experimental compound ameliorated symptoms ...
Aug 27, 2020
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Inflammation drives the progression of neurodegenerative brain diseases and plays a major role in the accumulation of tau proteins within neurons. An international research team led by the German Center for Neurodegenerative ...
Nov 20, 2019
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