German Center for Neurodegenerative Diseases

The German Center for Neurodegenerative Diseases (German: Deutsches Zentrum für Neurodegenerative Erkrankungen, DZNE) aims to develop new preventive and therapeutic approaches for neurodegenerative diseases. To accomplish this the DZNE follows a translational approach. This means that fundamental research is closely related to clinical research, population studies and health care research. In total there are nine sites all over Germany: Berlin, Bonn, Dresden, Göttingen, Magdeburg, Munich, Rostock / Greifswald, Tübingen and Witten. At each site the DZNE works closely with universities, university hospitals and other partners. The DZNE receives 90 percent of its funding from the Federal Ministry of Education and Research and 10 percent from the respective federal states containing DZNE sites.

Website
https://www.dzne.de/en/
Wikipedia
https://en.wikipedia.org/wiki/German_Center_for_Neurodegenerative_Diseases

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Genetics

Risk gene for Alzheimer's has early effects on the brain

A genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with certain memory tasks. Researchers from the German Center for Neurodegenerative Diseases (DZNE) and the Ruhr-Universität ...

Neuroscience

A tailor-made molecule that ties nerve connections

Researchers from the German Center for Neurodegenerative Diseases (DZNE), UK and Japan have developed a neurologically acting protein and tested it in laboratory studies. In mice, the experimental compound ameliorated symptoms ...

Neuroscience

Noise disturbs the brain's compass

Our sense of direction tends to decline with age. In the scientific journal Nature Communications, researchers from the German Center for Neurodegenerative Diseases (DZNE) and experts from the U.S. report on new insights ...

Neuroscience

Alzheimer research: Noise-inducing neurons shut down memories

Neurons that are responsible for new experiences interfere with the signals of neurons that contain memories and thereby disturb the recall of memories—at least in mice. The research group of Martin Fuhrmann of the German ...

Neuroscience

Brain diseases with molecular diversity

Parkinson's and multisystem atrophy (MSA), both neurodegenerative diseases, are associated with the accumulation of alpha-synuclein proteins in the brain. Researchers at the German Center for Neurodegenerative Diseases (DZNE) ...

Neuroscience

An immunological memory in the brain

Inflammatory reactions can change the brain's immune cells in the long term—meaning that these cells have an "immunological memory." This memory may influence the progression of neurological disorders that occur later in ...

Alzheimer's disease & dementia

Inflammation drives progression of Alzheimer's

According to a study published in the journal Nature by scientists of the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, inflammatory mechanisms caused by the brain's immune system drive the ...

Diseases, Conditions, Syndromes

COVID-19: German scientists lay basis for a passive vaccination

Researchers at the German Center for Neurodegenerative Diseases (DZNE) and Charité - Universitätsmedizin Berlin have identified highly effective antibodies against the coronavirus SARS-CoV-2 and are now pursuing the development ...

Medical research

Lumpy proteins stiffen blood vessels of the brain

Deposits of a protein called 'Medin,' which manifest in virtually all older adults, reduce the elasticity of blood vessels during aging and hence may be a risk factor for vascular dementia. Experts from the German Center ...

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