The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), situated on the Utrecht Science Park 'De Uithof'. Since 2008, the Hubrecht is affiliated with the UMC Utrecht.
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Cardiovascular diseases, such as heart attacks, are a leading cause of death worldwide resulting from a limited self-healing power of the heart. Unlike humans, zebrafish have the remarkable capacity to recover from cardiac ...
May 18, 2023
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Head and neck cancer (HNC) is an overarching term used for several types of cancer, including the most common form called head and neck squamous cell carcinoma (HNSCC). HNC patients can be treated with a combination of surgery, ...
May 12, 2023
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Mutations in genes that form the desmosome are the most common cause of the cardiac disease arrhythmogenic cardiomyopathy (ACM), which affects one in 2,000 to 5,000 people worldwide. Researchers from the group of Eva van ...
Mar 22, 2023
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Researchers from the group of Eva van Rooij in collaboration with the UMC Utrecht identified a new mutation that leads to the cardiac disease arrhythmogenic cardiomyopathy (ACM).
Mar 2, 2023
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Researchers from the Organoid group (former Clevers group, Hubrecht Institute) together with researchers from the Princess Máxima Center for pediatric oncology have established novel human organoid models of fatty liver ...
Feb 23, 2023
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Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids—miniature versions of the small intestine. This will help them to better study the functioning of the small ...
Aug 23, 2022
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Researchers from the group of Eva van Rooij at the Hubrecht Institute have used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced ...
May 24, 2022
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Hypertrophic cardiomyopathy is a heart disease that leads to a stressed, swollen heart muscle. Due to a poor understanding of underlying mechanisms, effective clinical treatments are not available. Patients receive generic ...
May 11, 2022
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Intestinal cells can change specializations during their lives. The BMP signaling pathway—an important communication mechanism between cells—appears to be the driver of these changes. That is what scientists from the ...
Mar 1, 2022
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The research groups of Jeroen Bakkers (Hubrecht Institute/UMC Utrecht) and Toon van Veen (UMC Utrecht) report the first patient-specific model for the heart disease arrhythmogenic cardiomyopathy (ACM). They were able to simulate ...
Dec 9, 2021
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