The availability of clinical trial records has increased markedly in recent years. For instance, several documents from numerous sources are often available for a single clinical trial—sometimes with overlapping, but often ...
Dec 11, 2020
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Autologous chondrocyte implantation (ACI) has been used in adults with deep cartilage defects for over 30 years and has been further developed and modified over time. For the most recent procedure, matrix-induced ACI (M-ACI), ...
Dec 7, 2020
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For heavy ex-smokers, lung cancer screening using low-dose computed tomography offers more benefit than harm: The procedure can save a number of people from dying of lung cancer; for some of them, it might also prolong overall ...
Dec 4, 2020
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The monoclonal antibody secukinumab is approved for the treatment of moderate to severe plaque psoriasis in children and adolescents from the age of six years who are candidates for systemic therapy. The German Institute ...
Dec 4, 2020
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Fostamatinib is approved for the treatment of chronic immune thrombocytopenia in adults who are refractory to other treatments (in particular to treatment with corticosteroids). The German Institute for Quality and Efficiency ...
Oct 6, 2020
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For certain surgical procedures, is there a correlation between the volume of services provided per hospital and the quality of treatment results? This is the question addressed in eight commissions that the Federal Joint ...
Oct 6, 2020
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In 2018 and 2019, the German Institute for Quality and Efficiency in Health Care (IQWiG) already investigated whether the drug enzalutamide has an advantage in comparison with the appropriate comparator therapy, i.e. in comparison ...
Aug 19, 2020
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Up to now, adult men with non-metastatic castration-resistant prostate cancer (nmCRPC) at high risk of developing metastatic disease usually continued their conventional androgen deprivation therapy (ADT) while the cancer ...
Aug 3, 2020
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The German Institute for Quality and Efficiency in Health Care (IQWiG) used an evidence map to investigate to what extent informative evidence exists on the benefit and harm of the diagnostic procedures 'non-invasive computed ...
Jul 8, 2020
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One of the consequences of diabetes mellitus, particularly if accompanied by high blood pressure (hypertension), can be a chronic kidney disease (diabetic nephropathy), which can lead to permanent failure of the kidneys (end-stage ...
Jul 6, 2020
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