A butterfly-shaped pigment accumulation in the macula of the eye, which can lead to severe vision loss in some patients, is due to mutations in the alpha-catenin 1 gene (CTNNA1), an international research consortium including ...
Dec 21, 2015
0
18
In work involving several new generations of mouse model development, Jackson Laboratory (JAX) researchers have tested a therapeutic intervention for spinal muscular atrophy (SMA) that restores some function lost due to a ...
Oct 14, 2015
0
56
A mutation that increases the level of a special class of sphingolipids—molecules important to cell structure and signaling—can lead to neurodegeneration due to problems with neuronal membranes, reports a research team ...
Oct 6, 2015
0
20
Studying the gastric cancers of 15 Southeast Asian patients, researchers at The Jackson Laboratory, the Genome Institute of Singapore and other institutions identified five recurrent fusion genes, one of which appears to ...
Jul 9, 2015
0
12
For Jackson Laboratory postdoctoral associate Danitza Nébor, Ph.D., studying sickle-cell disease isn't just a research project: It's a personal mission.
Jun 19, 2015
0
7
A Jackson Laboratory research team has found that the misfolded proteins implicated in several cardiac diseases could be the result not of a mutated gene, but of mistranslations during the "editing" process of protein synthesis.
Nov 24, 2014
1
0
A research team led by Jackson Laboratory Professors Frank McKeon, Ph.D., and Wa Xian, Ph.D., reports on the role of certain lung stem cells in regenerating lungs damaged by disease.
Nov 12, 2014
0
1
.jpg)
A research team led by Jackson Laboratory Professor and Howard Hughes Investigator Susan Ackerman, Ph.D., have pinpointed a surprising mechanism behind neurodegeneration in mice, one that involves a defect in a key component ...
Jul 24, 2014
1
0
Research aimed at developing germ cells—the progenitors of eggs and sperm—in vitro should be held to especially rigorous scientific standards, a distinguished team of reproductive biologists declares in the journal Cell.
Jun 11, 2014
0
0
A Jackson Laboratory research team led by Professor Lenny Shultz, Ph.D., reports that a protein involved in wound healing and tumor growth could be a potential therapeutic target.
May 12, 2014
0
0
