A research team led by Jackson Laboratory (JAX) Professor Karolina Palucka, M.D., Ph.D., in collaboration with a research team at Institut Curie in France led by Dr. Nicolas Manel, have addressed a long-standing puzzle of ...
Jul 7, 2017
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Combining single-cell genomics and computational techniques, a research team including Paul Robson, Ph.D., director of single-cell biology at The Jackson Laboratory (JAX), has defined cell-type composition of cancerous cells ...
Mar 20, 2017
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In mice genetically predisposed to glaucoma, vitamin B3 added to drinking water is effective at preventing the disease, a research team led by Jackson Laboratory Professor and Howard Hughes Medical Investigator Simon W.M. ...
Feb 16, 2017
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Some cancer cells have a trick up their sleeve to avoid cell death: boosting maintenance of telomeres, the protective "end caps" on chromosomes, and a research team led by Jackson Laboratory (JAX) Professor Roel Verhaak reports ...
Jan 30, 2017
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Every cancer starts with a single cell, and Jackson Laboratory (JAX) researchers have found a precise and reliable way—whole-genome profiling of open chromatin—to identify the kind of cell that leads to a given case of ...
Jul 11, 2016
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A research team led by Jackson Laboratory (JAX) President and CEO Edison Liu, M.D., have found a molecular fingerprint of some of the most deadly cancers of women: a genomic configuration described as a tandem duplicator ...
Apr 4, 2016
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Recent research has established associations between certain environmental factors, including eating a western diet and being sedentary, with an increased susceptibility to Alzheimer's disease. In fact, it is estimated that ...
Mar 7, 2016
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186
A butterfly-shaped pigment accumulation in the macula of the eye, which can lead to severe vision loss in some patients, is due to mutations in the alpha-catenin 1 gene (CTNNA1), an international research consortium including ...
Dec 21, 2015
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In work involving several new generations of mouse model development, Jackson Laboratory (JAX) researchers have tested a therapeutic intervention for spinal muscular atrophy (SMA) that restores some function lost due to a ...
Oct 14, 2015
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A Jackson Laboratory research team has found that the misfolded proteins implicated in several cardiac diseases could be the result not of a mutated gene, but of mistranslations during the "editing" process of protein synthesis.
Nov 24, 2014
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