Josep Carreras Leukaemia Research Institute is an International Research Institute whose mission is to investigate fundamental, epidemiological, preventive, clinical and translational aspects of leukemia, lymphoma, and other hematologic malignancies.
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Before the first oncogene mutations were discovered in human cancer in the early 1980s, the 1970s provided the first data suggesting alterations in the genetic material of tumors. In this context, the prestigious journal ...
Aug 12, 2020
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In autoimmunity, the mechanisms that guarantee that our defense system does not attack our own body—tolerance to oneself—does not work properly. Multiple sclerosis, which affects one in every 1,000 people in Spain, is ...
Jan 19, 2022
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Researchers from the Cancer Epigenetics group led by Dr. Manel Esteller at the Josep Carreras Leukaemia Research Institute and Dr. Aurora Pujol, from the Bellvitge Biomedical Research Institute (IDIBELL), have identified ...
Jun 27, 2022
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New research describes how highly proliferative leukemia cells end up becoming normal cells that no longer multiply, by changing the chemical modifications—the so-called epigenetics—of a type of its genetic material: ...
Jun 9, 2022
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All human tumors originating from various tissues share a series of properties that define them, including the ability to prevent cell death. Instead, healthy organs induce programmed cell death or apoptosis to balance their ...
Aug 1, 2022
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The immune system is one of the most complex parts of our body. It keeps us healthy by getting rid of parasites, viruses or bacteria, and by destroying damaged or cancer cells. One of its most intriguing abilities is its ...
Jul 13, 2023
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A recently published paper in the journal Molecular Cancer by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute, ICREA Research Professor and Genetics Chairman at the University ...
Feb 17, 2022
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Researchers of the Hospital Universitario 12 de Octubre in Madrid and the Josep Carreras Leukaemia Research Institute in Barcelona have developed a cell therapy for a type of leukemia which currently has very few treatment ...
Jan 16, 2023
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The abundance and function of blood vessels in adipose tissue conditions the development of obesity. This is the surprising conclusion reached by the study led by laboratories from the Josep Carreras Leukaemia Research Institute ...
Mar 15, 2022
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For a long time, cancer genetics and epigenetics researchers have been focusing on alterations in genes and proteins to understand what makes a cell turn cancerous and become malignant. In the nucleus of the cell, there is ...
Jan 25, 2023
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