Researchers have generated induced pluripotent stem cell (iPSC)-derived kidney organoids to model Alport syndrome caused by a mutation in the COL4A5 gene and have demonstrated the utility of a chemical chaperone to rescue ...
Oct 18, 2023
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Assistant Professor Shunsuke Funakoshi, Associate Professor Yoshinori Yoshida, and their research team have identified Am80 as a molecule that activates the cell cycle in cardiomyocytes to enhance cardiac tissue graft production ...
Jul 14, 2023
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Dopamine has been known to increase when results are promising and decrease when expectations are not met. However, this role does not explain the ability to overcome disappointment.
Jun 20, 2023
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A study published in the journal Stem Cell Reports on March 23, led by Dr. Ryosuke Tsuchimochi and Professor Jun Takahashi, examined the effects of combining cell transplantation and gene therapy for axonal outgrowth in the ...
Apr 10, 2023
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A new chip that holds different cell types in tiny, interconnected chambers could allow scientists to better understand the physiological and disease interactions between organs. The integrated-gut-liver-on-a-chip (iGLC) ...
Apr 7, 2023
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When our bodies become infected, various immune responses are triggered, starting with a release of granulocytes, white blood cells containing special enzymes that make up about half or more of all human white blood cells.
Mar 9, 2023
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SARS-CoV-2 infects and causes damage to multiple organs in COVID-19 patients. In particular, liver damage has been associated with COVID-19 severity. However, an understanding of the liver pathophysiology of these patients ...
Mar 8, 2023
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The function of the brain depends on the kind of circuit network it forms to enable perception and actions. No technology exists, however, to help reveal the structure of the hidden network by examining the neural activity ...
Feb 16, 2023
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The Yoko Hamazaki Laboratory at CiRA has reported that the slower onset of helper T-cell responses in the elderly after COVID-19 vaccinations is associated with lower antibody production, killer T cell activation, and frequency ...
Jan 13, 2023
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The Hidetoshi Sakurai Laboratory at CiRA has successfully reproduced the pathology of Myotonic Dystrophy type 1 (DM1) using skeletal muscle cells generated from patient-derived iPS cells and demonstrated their use for quantitative ...
Jan 12, 2023
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