The molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "double positive" CD4+-CD8+ T cells have lately been discovered in people in various ...
Sep 20, 2022
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A team led by Ludwig Stanford's Laura Attardi explored novel mechanisms by which the p53 protein, often called the guardian of the genome, regulates gene expression by looking for novel proteins that interact with the versatile ...
Sep 20, 2022
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Natural killer (NK) cells have lately become a hot focus of efforts to develop new immunotherapies. Researchers led by Ludwig Harvard's Tony Letai, whose team collaborated closely with the Ludwig Harvard Kai Wucherpfennig ...
Sep 20, 2022
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In a May publication in iScience, researchers led by Ludwig Johns Hopkins's Ashley Cook, Nicolas Wyhs, Kenneth Kinzler and Shibin Zhou described their creation of a panel of isogenic—or genetically identical—cell lines ...
Sep 20, 2022
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Researchers led by Ludwig Lausanne's Anoek Zomer, Davide Croci and Johanna Joyce described in a June publication in iScience their development of a multimodal imaging platform to explore, over extended periods, the changing ...
Sep 20, 2022
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A team led by Ludwig Lausanne's Tatiana Petrova, Jeremiah Bernier-Latmani and alum Christoph Cisarovsky identified a novel mechanism by which stem cells in intestinal tumors generate new blood vessels and evade anti-angiogenic ...
Sep 20, 2022
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In a new paper published in Nucleic Acids Research, a team led by Ludwig Oxford's Chunxiao Song reported a method for whole-genome long-read sequencing using TAPS (for Tet-assisted pyridine borane sequencing), the method ...
Sep 20, 2022
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The analysis of tissue samples for cancer diagnosis and treatment is still largely done under the light microscope. But researchers are now developing technologies to speed up and ultimately improve the accuracy of such diagnostics ...
Apr 21, 2022
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A Ludwig Cancer Research study has uncovered a cellular interaction that is essential to the ability of the immune system's cytotoxic T lymphocytes to destroy ovarian tumors and shown that its engagement could help determine ...
Nov 6, 2021
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A Ludwig Cancer Research study has identified a means by which cancer cells engineer the conversion of immune cells known as macrophages from destroyers of tumors to supporters of their growth and survival. The new research, ...
Oct 25, 2021
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