Mount Desert Island Biological Laboratory

Mount Desert Island Biological Laboratory (MDIBL) is a private, nonprofit biological research and education institution located in Salisbury Cove, Maine on Mount Desert Island, founded in 1898. Medical and Marine researchers as well as students from around the world spend their summers at MDIBL studying the basic biological mechanisms of cold-water marine organisms. MDIBL has offered a unique culture of informality and scientific rigor from its inception. Students, scientists and physicians participating in MDIBL programs live on the oceanside campus, immersing themselves in scientific inquiry and collaboration. Discoveries made at MDIBL have led to advances in diagnosing and treating cyctic fibrosis, cancer, glaucoma, macular degeneration, heart disease, and liver and kidney disorders. The work done at MDIBL has also led to a better understanding of the effects of environmental toxins on health.


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Diseases, Conditions, Syndromes

Scientist identifies process critical to kidney function

Our kidneys are charged with the extraordinary task of filtering about 53 gallons of fluid a day, a process that depends on podocytes, which are tiny, highly specialized cells in the cluster of blood vessels in the kidney ...


Scientists decipher role of a stress response gene

Scientists have long known that chronic stress experienced early in life, or even chronic prenatal exposure to maternal stress hormones in the womb, can shorten lifespan and contribute to age-related chronic diseases like ...

Medical research

Biological laboratory scientist develops new imaging method

The extraordinary progress that has been achieved in the biomedical sciences in the modern era can be attributed in large measure to imaging technologies that have allowed scientists to observe the structure and function ...

Medical research

Scientists identify new genetic regulators of regeneration

Scientists at the MDI Biological Laboratory and the University of Maine have discovered that genetic material in the cell that was previously thought to be "junk" because of its apparent lack of function likely plays a part ...


Discovery could lead to new therapies for diabetics

New research by MDI Biological Laboratory scientist Sandra Rieger, Ph.D., and her team has demonstrated that an enzyme she had previously identified as playing a role in peripheral neuropathy induced by cancer chemotherapy ...

Medical research

Study finds immune system is critical to regeneration

The answer to regenerative medicine's most compelling question—why some organisms can regenerate major body parts such as hearts and limbs while others, such as humans, cannot—may lie with the body's innate immune system, ...

Medical research

Research sheds light on mechanisms underlying aging

Scientists have known for decades that drastically restricting certain nutrients without causing malnutrition prolongs health and lifespan in a wide range of species, but the molecular mechanisms underlying this effect have ...

Psychology & Psychiatry

Research examines role of early-life stress in adult illness

Scientists have long known that chronic exposure to psychosocial stress early in life can lead to an increased vulnerability later in life to diseases linked to immune dysfunction and chronic inflammation, including arthritis, ...

Medical research

New mechanism for wound healing identified

Wound healing is not a one-size-fits-all process. MDI Biological Laboratory Assistant Professor, Vicki P. Losick, Ph.D, has recently discovered a new healing mechanism, which she has called wound-induced polyploidy (WIP).

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