Mount Desert Island Biological Laboratory

Mount Desert Island Biological Laboratory (MDIBL) is a private, nonprofit biological research and education institution located in Salisbury Cove, Maine on Mount Desert Island, founded in 1898. Medical and Marine researchers as well as students from around the world spend their summers at MDIBL studying the basic biological mechanisms of cold-water marine organisms. MDIBL has offered a unique culture of informality and scientific rigor from its inception. Students, scientists and physicians participating in MDIBL programs live on the oceanside campus, immersing themselves in scientific inquiry and collaboration. Discoveries made at MDIBL have led to advances in diagnosing and treating cyctic fibrosis, cancer, glaucoma, macular degeneration, heart disease, and liver and kidney disorders. The work done at MDIBL has also led to a better understanding of the effects of environmental toxins on health.


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Medical research

Scientists identify new genetic regulators of regeneration

Scientists at the MDI Biological Laboratory and the University of Maine have discovered that genetic material in the cell that was previously thought to be "junk" because of its apparent lack of function likely plays a part ...


Discovery could lead to new therapies for diabetics

New research by MDI Biological Laboratory scientist Sandra Rieger, Ph.D., and her team has demonstrated that an enzyme she had previously identified as playing a role in peripheral neuropathy induced by cancer chemotherapy ...

Medical research

Study finds immune system is critical to regeneration

The answer to regenerative medicine's most compelling question—why some organisms can regenerate major body parts such as hearts and limbs while others, such as humans, cannot—may lie with the body's innate immune system, ...

Medical research

Research sheds light on mechanisms underlying aging

Scientists have known for decades that drastically restricting certain nutrients without causing malnutrition prolongs health and lifespan in a wide range of species, but the molecular mechanisms underlying this effect have ...

Psychology & Psychiatry

Research examines role of early-life stress in adult illness

Scientists have long known that chronic exposure to psychosocial stress early in life can lead to an increased vulnerability later in life to diseases linked to immune dysfunction and chronic inflammation, including arthritis, ...

Medical research

New mechanism for wound healing identified

Wound healing is not a one-size-fits-all process. MDI Biological Laboratory Assistant Professor, Vicki P. Losick, Ph.D, has recently discovered a new healing mechanism, which she has called wound-induced polyploidy (WIP).


Scientist identifies mechanism underlying peripheral neuropathy

Recent research by Sandra Rieger, Ph.D., of the MDI Biological Laboratory identifying the underlying mechanisms of peripheral neuropathy, or nerve damage, has raised the prospect that drug therapies can be developed for the ...

Medical research

Scientist identifies mechanism to regenerate heart tissue

The MDI Biological Laboratory has announced new discoveries about the mechanisms underlying the regeneration of heart tissue by Assistant Professor Voot P. Yin, Ph.D., which raise hope that drugs can be identified to help ...