Page 12 - RIKEN

Genetics

Genes that regulate how much we dream

Sleep is known to re-energize animals and consolidate their memories. Rapid eye movement (REM) sleep, a mysterious stage of sleep in which animals dream, is known to play an important role in maintaining a healthy mental ...

Neuroscience

Mouse memory cells are about experience, not place

When it comes to memory, it's more than just "location, location, location." New research suggests that the brain doesn't store all memories in place cells, the main type of neuron in the hippocampus, a structure crucial ...

Psychology & Psychiatry

Mutation links bipolar disorder to mitochondrial disease

Mutations in the gene ANT1 may confer a risk for bipolar disorder through a complex interplay between serotonin and mitochondrial signaling in the brain. These two pathways have been separately implicated in bipolar disorder, ...

Neuroscience

Gene linked to intellectual ability affects memory replay in mice

Researchers at the RIKEN Center for Brain Science in Japan have discovered that a gene associated with human intellectual ability is necessary for normal memory formation in mice. Published in Nature Neuroscience, the study ...

Alzheimer's disease & dementia

Mutation discovered to protect against Alzheimer's disease in mice

Researchers at the RIKEN Center for Brain Science have discovered a mutation that can protect against Alzheimer's disease in mice. Published in the scientific journal Nature Communications, the study found that a specific ...

Oncology & Cancer

Vitamin A derivative selectively kills liver cancer stem cells

Acyclic retinoid, an artificial compound derived from vitamin A, has been found to prevent the recurrence of hepatocellular carcinoma (HCC), the most common form of liver cancer. Now, in research published in Proceedings ...

Immunology

Researchers uncover origin of virus-fighting plasma B cells

Plasma B cells, which move through the body releasing antibodies, are an important component of the body's fight against viral infections and other invaders. They are relatively rare, however, and increasing their ranks is ...

Neuroscience

The brain's GPS has a buddy system

To be successful as a social animal, you need to know where you stand relative to others. Brain cells that perform precisely this function—locating the 'self' and others in space—have now been identified. In rats, the ...

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