Sanford Burnham Prebys Medical Discovery Institute

Diseases, Conditions, Syndromes

Path to deadly sepsis varies by bacterial infection

Sepsis remains a common and deadly condition that occurs when the body reacts to an infection in the bloodstream. Scientists know little about the early stages of the condition; however, physicians must act fast. Every hour ...

Medical research

Mannose's unexpected effects on the microbiome and weight gain

Scientists continue to unravel links between body weight and the gut microbiome. Now, researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP) report an unexpected finding: mice fed a fatty diet and mannose, ...

Inflammatory disorders

Solving the gut inflammation puzzle

Inflammatory bowel disease (IBD), an umbrella term for a number of gut disorders—including ulcerative colitis and Crohn's disease—remains a clinical challenge. Current treatments don't work for all patients, and many ...

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