To speed progress against cancer and other diseases, the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project today announced the largest-ever release of comprehensive human cancer ...
May 29, 2012
0
0
The protein Foxp3 is vital to the function of immune cells called regulatory T cells, which control immune system activation. Despite its importance, how Foxp3 regulates the immune system using environmental cues has remained ...
Jun 27, 2024
0
32
Understanding the molecular characteristics of cancer that impact patient outcomes is essential to identifying novel treatment strategies for the most intractable pediatric malignancies. Many of these diseases are difficult ...
Jun 26, 2024
0
0
Survivors of childhood cancer are at increased risk for cardiovascular disease, for which a risk factor is their greater prevalence of type 2 diabetes, with a disproportionate impact on those of non-European heritage. St. ...
Apr 24, 2024
0
24
Scientists from St. Jude Children's Research Hospital today announced the St. Jude survivorship portal—the first data portal for sharing, analyzing and visualizing pediatric cancer survivorship data.
Apr 9, 2024
0
0
Resistance to chemotherapy is typically associated with poor outcomes for patients with cancer. However, St. Jude Children's Research Hospital scientists demonstrated that in bilateral Wilms tumor (cancer in both kidneys) ...
Mar 28, 2024
0
0
The life and death of cells are governed by processes that—when disrupted—can lead to cancer. Apoptosis, the process of programmed cell death, is tightly regulated by the B-cell lymphoma-2 (BCL-2) family of proteins. ...
Mar 18, 2024
0
0
Hemophagocytic lymphohistiocytosis (HLH) is a rare and often aggressive syndrome of hyperactive inflammation with up to a 40% mortality rate. Scientists at St. Jude Children's Research Hospital have shown that a drug inhibiting ...
Mar 6, 2024
0
0
The protein HOXA9 is overexpressed in most acute myeloid leukemia (AML) cases and is associated with poor patient outcomes. However, HOXA9 is a difficult protein to target therapeutically, so researchers at St. Jude Children's ...
Jan 12, 2024
0
0
Data from the St. Jude lifetime cohort study (St. Jude LIFE) have revealed that two common biomarkers of cardiac function and damage could better predict cardiomyopathy within five years than routine clinical evaluations ...
Jan 11, 2024
0
1
