Researchers have discovered that inhibiting CDK9, a DNA transcription regulator, reactivates genes that have been epigenetically silenced by cancer. Reactivation leads to restored tumor suppressor gene expression and enhanced ...
Oct 25, 2018
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Genetic testing is a powerful diagnostic tool that is increasingly being used for the diagnosis of dilated cardiomyopathy, a disease in which the heart becomes enlarged, making it difficult to pump blood. Cardiomyopathy affects ...
Aug 22, 2018
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Deep vein thrombosis (DVT) is a common medical condition in which blood clots develop in the deep veins of the body, often in the legs, thigh or pelvis. These clots can break loose and travel to the lungs and can cause a ...
Jul 16, 2018
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Proteins commonly known as BRCA—short for BReast CAncer susceptibility gene- serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating cancer development. If the ...
Jun 12, 2018
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Reversing memory deficits and impairments in spatial learning is a major goal in the field of dementia research. A lack of knowledge about cellular pathways critical to the development of dementia, however, has stood in the ...
Jun 8, 2018
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For patients with severe emphysema, every breath brings equal parts relief and burden. Oxygenated air comes in, but not all the air from the last breath is exhaled. Rather, it becomes trapped in the lungs, caught in large ...
May 22, 2018
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The amino acid homocysteine occurs naturally in the human body, generated as a byproduct of methionine metabolism. Genetic diseases or an imbalanced diet, with too much red meat or deficiencies in B vitamins and folic acid, ...
May 16, 2018
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Canola oil is one of the most widely consumed vegetable oils in the world, yet surprisingly little is known about its effects on health. Now, a new study published online December 7 in the journal Scientific Reports by researchers ...
Dec 7, 2017
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Endotracheal intubation, in which a tube is inserted through the voice box (larynx) into the windpipe, and tracheotomy, in which surgery is undertaken to create a hole through the neck and into the windpipe (trachea) to facilitate ...
Nov 22, 2017
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Almost a century ago, scientists discovered that cutting calorie intake could dramatically extend lifespan in certain animal species. Despite numerous studies since, however, researchers have been unable to explain precisely ...
Sep 14, 2017
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