Melanoma patients who receive treatment with targeted therapies experience an initial response that feels like a cure, but that early excitement is quickly dampened when patients relapse as their cancers find alternative ...
Jan 7, 2016
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More than half of all people infected by the HIV-1 virus worldwide are women. Commercial sex workers, who are at increased risk of contracting HIV because of repeated exposure to the virus, have long been studied to test ...
Dec 9, 2015
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The gene SPOP is mutated in up to 15 percent of all cases of prostate cancer, making it one of the most mutated genes in the disease. However, when the gene is functioning properly, it acts as a tumor suppressor. Despite ...
Oct 29, 2015
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The enzyme phosphatidylinositol-3 kinase (PI3K) appears to be exploited in almost every type of human cancer, making it the focus of considerable interest as a therapeutic target, with many PI3K-inhibiting drugs currently ...
Jun 29, 2015
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Viruses like influenza have the ability to mutate over time, and given that the flu vaccines administered during the 2014-2015 season were largely ineffective at preventing the spread of the flu, it appears the virus that ...
Jun 25, 2015
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Survival rates for patients with lung cancer increase dramatically the earlier the disease is diagnosed, underscoring the need for effective biomarkers that can be used for detection. Now, scientists at The Wistar Institute ...
Jun 3, 2015
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Senescence, a phenomenon in which cells cease to divide and grow, can be caused by everything from natural DNA damage to treatment with chemotherapy. However, several mechanisms allow for cells to bypass senescence and grow ...
Jun 2, 2015
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In recent years, research has shown that cancerous cells have a different metabolism—essential chemical and nutritional changes needed for supporting the unlimited growth observed in cancer—than normal cells. Now, scientists ...
Apr 30, 2015
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In the last several years, targeted therapies - drugs that directly impact specific genes and proteins involved in the progression of cancer - have been approved for a wide variety of cancers, including melanoma, the deadliest ...
Mar 17, 2015
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Ovarian cancer is the deadliest of all cancers affecting the female reproductive system with very few effective treatments available. Prognosis is even worse among patients with certain subtypes of the disease. Now, researchers ...
Feb 16, 2015
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