Immunology
Impaired neutrophils in autoimmunity
Patients with autoimmune diseases such as systemic lupus erythematosus (SLE) have higher blood levels of the protein S100A9, but the source of this protein has not been identified.
Jan 28, 2022
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6
Vanderbilt University
Diseases, Conditions, Syndromes
Study: Omicron evades some but not all monoclonal antibodies
Several, but not all, of the human monoclonal antibodies used clinically to prevent patients from becoming severely ill from COVID-19 may not be protective against the omicron variant now sweeping across the United States, ...
Jan 21, 2022
2
146
Medications
Autoimmune drug shows promise in treating severe burns
A severe burn injury is not static. Within 72 hours, partial thickness burns can progress, or convert, to full thickness burns, greatly increasing the risk of infection, incapacitating scarring, and even death.
Jan 13, 2022
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2
Medications
Antibodies for prevention of COVID-19 granted FDA emergency use authorization
On Wednesday, the U.S. Food and Drug Administration granted emergency use authorization (EUA) to the global biopharmaceutical company AstraZeneca for a long-acting antibody combination which protects against COVID-19, discovered ...
Dec 13, 2021
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4
Oncology & Cancer
Cell signaling targets in leukemia
Mutations in the enzyme IDH (isocitrate dehydrogenase) are found in 15–20% of acute myeloid leukemia (AML) cases. IDH mutations have been shown to impact cellular differentiation and DNA and histone methylation, but little ...
Dec 13, 2021
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2
Oncology & Cancer
Study: Prostate cancer treatment regret
More than one in 10 patients with localized prostate cancer experience treatment-related regret—a sense of disappointment with their treatment compared to other treatment options—according to a recent study published ...
Dec 13, 2021
0
0
Psychology & Psychiatry
A potential new approach for the treatment of schizophrenia
A new study led by Jeff Conn, Lee E. Limbird Chair in Pharmacology, James Maksymetz, a former graduate student in the Conn laboratory, and other collaborators at the Warren Center for Neuroscience Drug Discovery has identified ...
Dec 8, 2021
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31
Psychology & Psychiatry
Study links depression scores, white blood cell count
Researchers across four health care systems, including Vanderbilt University Medical Center, have found that increased depression polygenic scores are associated with increased white blood cell count, highlighting the importance ...
Dec 3, 2021
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55
Medications
Study provides new insight into how antidepressant drugs work
New details reported in Science Translational Medicine by a team at Vanderbilt University Medical Center shed light on how current antidepressant drugs work and suggest a new drug target in depression.
Dec 3, 2021
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86
Biomedical technology
New study reveals breakthrough tool to show how much exoskeletons reduce back injury risk
A study led by researchers from Vanderbilt University's Center for Rehabilitation Engineering and Assistive Technology reveals a breakthrough tool to assess the effect of exoskeletons on injury risk.
Nov 30, 2021
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3
