Vanderbilt University

Mitochondrial mutations and disease

Mitochondria are cellular organelles with their own DNA. Their role in power generation makes them susceptible to oxidative damage, including the formation of DNA-damaging chemical complexes called adducts.

10 hours ago
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A new target for neuroblastoma

Neuroblastoma, a cancer that starts in nerve tissue outside of the brain, is the third most common cancer in children and accounts for about 15 percent of pediatric cancer-related deaths.

Feb 15, 2018
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Cognition in rare hormonal disorder

PHP1A (pseudohypoparathyroidism 1A) is a rare genetic disorder that causes short adult stature, multi-hormone resistance, early-onset obesity and cognitive impairment.

Feb 14, 2018
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Protecting transplanted lungs

Primary graft dysfunction (PGD)—acute lung injury that develops within 72 hours of lung transplantation—is a major cause of illness and death after transplant. The mechanisms leading to PGD are not well understood, and ...

Feb 13, 2018
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Muscular dystrophy clue

Patients with Duchenne muscular dystrophy (DMD) have a genetic mutation that causes incurable muscle degeneration. Research has shown that the immune system plays a complex, double-sided role in muscular dystrophy—promoting ...

Feb 12, 2018
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Study evaluates community-based health efforts

A new study from researchers at Vanderbilt and Harvard universities, published this week in the journal Health Affairs, uses federal health survey data to evaluate community-based efforts to address smoking, obesity and other ...

Feb 05, 2018
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