In 2018, a 31-year-old woman checked into Massachusetts General Hospital (MGH) in Boston with a respiratory infection so bad she had to be placed on oxygen. A trip to the hospital for lung trouble was nothing new for her—several ...
Apr 23, 2020
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164
Multiple sclerosis (MS) is a debilitating disease in which the body's own immune system attacks itself and can, over time, permanently destroy the protective sheaths, or myelin, around nerve fibers in the brain. Myelin insulates ...
Apr 6, 2020
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150
In a new paper published March 5 in the journal Cell Stem Cell, researchers in Whitehead Institute Member Rudolph Jaenisch's lab introduce a new way to model human neuroblastoma tumors in mice using chimeras—in this case, ...
Mar 6, 2020
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165
The cells of most patients' cancers are resistant to a class of drugs, called proteasome inhibitors, that should kill them. When studied in the lab, these drugs are highly effective, yet hundreds of clinical trials testing ...
May 28, 2019
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185
Three years after the Zika virus swept through tropical and subtropical South America, the Caribbean, Florida, and Texas, much remains unknown about what the virus needs to infect and damage its host cells in the brain. Now ...
Apr 23, 2019
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28
Red blood cells are the most plentiful cell type in our blood and play a vital role transporting oxygen around our body and waste carbon dioxide to the lungs. Injuries that cause significant blood loss prod the body to secrete ...
Mar 1, 2019
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101
A team of researchers at Whitehead has illuminated an important role for different subtypes of muscle cells in orchestrating the process of tissue regeneration. In a paper published in the November 22 issue of Nature, they ...
Nov 22, 2017
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166
A team of scientists led by Whitehead Institute has uncovered a surprising molecular link that connects how cells regulate growth with how they sense and make available the nutrients required for growth. Their work, which ...
Oct 19, 2017
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3
For the first time, Whitehead Institute scientists have documented a direct link between deletions in two genes—fam57ba and doc2a—in zebrafish and certain brain and body traits, such as seizures, hyperactivity, enlarged ...
Oct 6, 2017
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109
For more than a century, physicians have anecdotally noted that patients with an underactive thyroid—often caused by iodine deficiency—tended to also have anemia. But the link between thyroid hormone and red blood cell ...
Sep 5, 2017
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