The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, but they don't work for up to 4 of every 10 patients.
Jan 30, 2026
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Our immune system has a dark side: It's supposed to fight off invaders to keep us healthy. But sometimes it turns traitor and attacks our own cells and tissues.
Nov 6, 2025
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Scientists have mapped underappreciated scaffolding cells in skin, known as fibroblasts. They show for the first time how fibroblasts go 'rogue' in many different diseases affecting multiple organs—from acne and psoriasis, ...
Sep 24, 2025
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Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don't work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes ...
Nov 26, 2025
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A new study, led by experts at the University of Nottingham, has found that medicines used to treat gout can also reduce the risk of heart attack and stroke in people with gout.
Jan 26, 2026
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In lupus nephritis, attainment of complete renal response (CRR)/partial renal response (PRR) and lupus low disease activity state (LLDAS) is associated with best relapse-free survival, with independent associations seen with ...
Aug 14, 2025
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Methotrexate, a common medication used to treat rheumatoid arthritis, has a newly recognized useful secondary effect of lowering blood pressure and potentially reduces the risk of heart disease in people with this condition.
Sep 3, 2025
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For the first time, scientists have used a modern cell therapy called CAR-T to treat a patient with three different life-threatening autoimmune diseases that had resisted years of treatment. The patient, who once required ...
Apr 9, 2026
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Researchers from the University of Birmingham, U.K., have identified bioactive peptide sequences in the PEPITEM molecule, and demonstrated the biological activity of the full PEPITEM molecule in counteracting key changes ...
Sep 2, 2025
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UCSF researchers have found that certain antiviral genes become less active over time in lupus, revealing why some patients see their symptoms fade as they age.
Jul 29, 2025
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