CAR T-cell therapy shows early promise in severe lupus

Early results from a UCL- and UCLH-led clinical trial suggest that a type of CAR T-cell therapy—developed by Autolus Therapeutics, a UCL spinout—could offer a new treatment approach for people with severe, treatment-resistant ...

Approved IV drug reduces lupus symptoms, clinical trial finds

An already-approved IV drug significantly reduces the symptoms of lupus, a new clinical trial showed. More than three-quarters of lupus patients taking obinutuzumab (Gazvya) had a significant improvement in their symptoms ...

High levels of gut bacterial toxin trigger lupus nephritis

The body's immune reaction to increased levels of a toxic molecule, part of a bacterial species in the human gut, may reveal who is most at risk of developing lupus nephritis, according to a new study led by NYU Langone Health. ...

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