Medical research

New powerful tool measures metabolites in living cells

By engineering cells to express a modified RNA called "Spinach," researchers have imaged small-molecule metabolites in living cells and observed how their levels change over time. Metabolites are the products of individual ...

Oncology & Cancer

Jak of all trades? Not of leukaemia therapy

About one in five or six cases of adult leukaemia in Western populations relates to so-called chronic myeloid leukaemia, or CML. Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition ...

Oncology & Cancer

Revised staging system prognostic for multiple myeloma

(HealthDay)—The International Staging System (ISS) combined with chromosomal abnormalities (CA) detected by interphase fluorescent in situ hybridization after CD138 plasma cell purification and serum lactate dehydrogenase ...

Psychology & Psychiatry

Risk of psychotic disorders has disease-specific brain effects

Brain abnormalities in people at familial risk of schizophrenia and bipolar disorder emerge in unique patterns, despite the symptom and genetic overlap of the disorders, according to a study in Biological Psychiatry. Similarities ...

Oncology & Cancer

Stem cells central to pathogenesis of mature lymphoid tumors

New research suggests that blood stem cells can be involved in the generation of leukemia, even when the leukemia is caused by the abnormal proliferation of mature cells. The study, published by Cell Press in the August 16th ...

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