A joint study on the Lynx1 protein has revealed that the protein competes with human nicotinic acetylcholine receptors for binding to amyloids, which are the main cause of Alzheimer's development. In the future, the protein ...
Jul 6, 2016
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A new study from Western University is helping to explain why the long-term use of common anticholinergic drugs used to treat conditions like allergies and overactive bladder lead to an increased risk of developing dementia ...
Jun 22, 2016
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Nicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due to their demonstrated role in processes underlying cognition ...
Jun 17, 2016
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Many people who smoke want to quit, but the urge to light up is often irresistible. An effective vaccine to help people kick the habit once and for all has been elusive. But now, scientists report in ACS' Journal of Medicinal ...
Mar 9, 2016
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A new study from Karolinska Institutet shows that amyloid-β-peptides, which are thought to be toxic and a suspected cause of Alzheimer's disease, actually have a biological function. The discovery, which is published in ...
Nov 4, 2015
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An international team of researchers, led by scientists at the National University of Singapore (NUS), has identified a protein that regulates the growth of neurons by transporting key metabolic enzymes to the tips of neural ...
Sep 21, 2015
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Brain researchers have been working for years on targeting a cellular process involved in neurodegeneration and cognitive dysfunction. A specialized molecular imaging agent does the job by binding to a transporter of the ...
Jun 8, 2015
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Menthol acts in combination with nicotine to desensitize the type of nicotinic receptors found in lungs and airways that are responsible for nicotine's irritation, say Georgetown University Medical Center (GUMC) researchers.
May 11, 2015
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Researchers at MIT's Picower Institute for Learning and Memory have shown for the first time that a common neurotransmitter acts via a single type of neuron to enable the brain to process information more effectively. The ...
Apr 28, 2015
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Nicotine's primary metabolite supports learning and memory by amplifying the action of a primary chemical messenger involved in both, researchers report.
Feb 18, 2015
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