Alzheimer's disease develops over decades. It begins with a fatal chain reaction in which masses of misfolded beta-amyloid proteins are produced that in the end literally flood the brain. Researchers including Mathias Jucker ...
Nov 17, 2020
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In many neurodegenerative diseases like Parkinson's, protein aggregates form in the brain and are assumed to contribute to neuronal cell death. Yet there exists a cellular defense mechanism that counteracts these aggregates, ...
Nov 11, 2020
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Alzheimer's disease is the leading cause of dementia worldwide and a major cause of disability. Now, researchers at Osaka University and Hokkaido University have shown that repeated precipitation-dissolution events of salt ...
Jul 27, 2020
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Changes in blood platelets triggered by COVID-19 could contribute to the onset of heart attacks, strokes, and other serious complications in some patients who have the disease, according to University of Utah Health scientists. ...
Jun 30, 2020
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A master control region of a protein linked to Parkinson's disease has been identified for the first time.
Mar 9, 2020
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Utrecht scientists have uncovered how aggregates alter the behavior of Tau protein, known to play a role in Alzheimer's disease. On a molecular level, the researchers have revealed why certain proteins tend to bind to Tau ...
Jan 31, 2020
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West Nile virus (WNV) inhibits autophagy to induce the aggregation of proteins in infected cells, triggering cell death and brain inflammation (encephalitis), according to Hokkaido University researchers. They also discovered ...
Jan 23, 2020
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Neurodegenerative diseases such as Alzheimer's and Parkinson's can be devastating to patients and their families. These diseases are difficult to diagnose before symptoms show, meaning it's often already too late to reverse ...
Dec 17, 2019
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Protein aggregates have been observed in the nerve tissue of patients with Parkinson's disease which consist of individual components (monomers) of the protein α-synuclein which assemble into what are referred to as amyloid ...
Sep 3, 2019
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Protein aggregation—in which misfolded proteins clump together to form large fibrils—has been implicated in many diseases including Alzheimer's, Parkinson's, and type II diabetes. While the exact role these fibrils play ...
Aug 16, 2019
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