Neuroscience
Scientists add to theory about Huntington's mechanism
Rice University researchers are starting to understand how protein fragments influence the fiber aggregation suspected as a cause of Huntington's disease.
Apr 10, 2017
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News tagged with aggregation
Medical research
Research identifies cellular recycling process linked to beneficial effects of enduring mild stress
Biologists have known for decades that enduring a short period of mild stress makes simple organisms and human cells better able to survive additional stress later in life. Now, scientists at Sanford Burnham Prebys Medical ...
Feb 15, 2017
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Medical research
Diagnosing disease before it reveals its presence
A vast class of incurable neurodegenerative disorders are characterized by the aggregation and deposition of aberrant proteins like the amyloid b peptide or a-synuclein, considered to be factors behind the development of ...
Sep 21, 2016
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Alzheimer's disease & dementia
Alzheimer's beginnings prove to be a sticky situation
Laser technology has revealed a common trait of Alzheimer's disease - a sticky situation that could lead to new targets for medicinal treatments.
Sep 12, 2016
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Parkinson's & Movement disorders
Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes
Scientists from the Institut Pasteur have demonstrated the role of lysosomal vesicles in transporting α-synuclein aggregates, responsible for Parkinson's and other neurodegenerative diseases, between neurons. These proteins ...
Aug 22, 2016
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Genetics
Shedding new light on protein aggregates and the diseases they cause
Researchers from the Massachusetts Institute of Technology and Boston University have developed a system capable of quickly screening millions of yeast cells to measure protein aggregates. Proteins regulate all of the processes ...
Jul 13, 2016
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Alzheimer's disease & dementia
Diagnosing Alzheimer's earlier rather than later
A hallmark of Alzheimer's disease is the appearance of plaques in the brain. The plaques are gradually made up by the aggregation of a small protein called amyloid-beta or "Abeta". Alzheimer's is usually diagnosed late, when ...
May 9, 2016
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Diseases, Conditions, Syndromes
New TB clinical trial data-sharing platform available for researchers
The Critical Path Institute (C-Path), the Special Programme for Research and Training in Tropical Diseases (TDR), TB Alliance, and St. George's, University of London, are pleased to announce the launch of the TB-Platform ...
Apr 18, 2016
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Medical research
Observing brain diseases in real time
An innovative tool allows researchers to observe protein aggregation throughout the life of a worm. The development of these aggregates, which play a role in the onset of a number of neurodegenerative diseases, can now be ...
Feb 15, 2016
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Neuroscience
ALS protein dynamics highlight delicate balance between self-association and aggregation
The ALS-related protein TDP-43 takes the first steps toward pathologic aggregation as part of its normal function, according to a new study publishing in the Open Access journal PLOS Biology on Jan. 6, 2016. The study, by ...
Jan 6, 2016
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