Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have characterized the mechanism that initiates the pathological aggregation of the protein FUS, which plays a central role in two distinct neurodegenerative diseases.
Apr 20, 2018
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A common thread ties seemingly unlinked disorders like Alzheimer's disease and type II diabetes together. This thread is known as protein aggregation and happens when proteins clump together. These complexes are a hallmark ...
Oct 22, 2017
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NUS biologists have discovered that dynamics of the FUS protein plays a key role in FUS proteinopathy that causes certain neurological diseases.
Jul 20, 2017
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Members of the Faculty of Fundamental Medicine at the Lomonosov Moscow State University have determined the structure of a peptide complex formed in the brain at the early stages of Alzheimer's disease. The research results ...
Jul 17, 2017
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In a recent Frontiers in Aging Neuroscience paper, Drs. Della David and Frank Baumann together with their teams at the German Center for Neurodegenerative Diseases and Hertie Institute, showed that changes in proteins associated ...
May 17, 2017
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Rice University researchers are starting to understand how protein fragments influence the fiber aggregation suspected as a cause of Huntington's disease.
Apr 10, 2017
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Biologists have known for decades that enduring a short period of mild stress makes simple organisms and human cells better able to survive additional stress later in life. Now, scientists at Sanford Burnham Prebys Medical ...
Feb 15, 2017
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A vast class of incurable neurodegenerative disorders are characterized by the aggregation and deposition of aberrant proteins like the amyloid b peptide or a-synuclein, considered to be factors behind the development of ...
Sep 21, 2016
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Laser technology has revealed a common trait of Alzheimer's disease - a sticky situation that could lead to new targets for medicinal treatments.
Sep 12, 2016
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Scientists from the Institut Pasteur have demonstrated the role of lysosomal vesicles in transporting α-synuclein aggregates, responsible for Parkinson's and other neurodegenerative diseases, between neurons. These proteins ...
Aug 22, 2016
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