Medical research

Restoring airway integrity in cystic fibrosis patients

Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure. It is caused by mutations in the CFTR ...

Diseases, Conditions, Syndromes

A respiratory model of COVID-19, made from patient-derived stem cells

What happens in our respiratory tract once we're exposed to COVID-19? A three-dimensional airway model, made from patient-derived stem cells, could provide answers about the initial stages of infection. The model not only ...

Diseases, Conditions, Syndromes

Cystic fibrosis faithfully modeled in a human Lung Airway Chip

The inherited progressive disorder cystic fibrosis (CF) causes severe damage to the lungs, and other tissues in the body by affecting the cells that produce mucus, sweat, and digestive juices. In individuals carrying mutations ...

Genetics

Gene changes might explain long-haul COVID-19 symptoms

Results from a new cell study suggest that the SARS-CoV-2 spike protein can bring about long-term gene expression changes. The findings could help explain why some COVID-19 patients—referred to as COVID long-haulers—experience ...

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