Research by scientists at Dignity Health St. Joseph's Hospital and Medical Center's Norton Thoracic Institute was published in the July 12, 2017 issue of Science Translational Medicine titled "Zbtb7a induction in alveolar ...
Jul 13, 2017
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Using CRISPR gene editing, a team from Children's Hospital of Philadelphia (CHOP) and Penn Medicine have thwarted a lethal lung disease in an animal model in which a harmful mutation causes death within hours after birth. ...
Apr 17, 2019
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University of Calgary scientists have discovered how to capture "live" images of immune cells inside the lungs. The group at the Snyder Institute for Chronic Diseases at the Cumming School of Medicine is the first in the ...
Sep 3, 2020
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Matters of the heart can sometimes be resolved from within. Pulmonary arterial hypertension, or PAH, caused by a thickening of the arterial walls and narrowing of the lumen can be fatal if left untreated. The use of vasodilators ...
Sep 7, 2022
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Idiopathic pulmonary fibrosis is a devastating disease, and recently approved therapies have limited efficacy. Lungs become damaged with fibrotic scarring, and the median length of survival after diagnosis is three to five ...
Feb 24, 2016
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It is becoming increasingly clear that the human microbiome—the collection of bacteria, viruses and fungi that live on and within us—significantly contributes to our health. Indeed, several recent studies have demonstrated ...
Feb 16, 2022
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Researchers have now grown lung organoids from human embryonic stem cells (hESCs) that, after implantation in mice, can develop mature alveolar type 1 (AT1) and AT2 cells and architecture approximating that of human lungs. ...
Sep 11, 2018
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Researchers from Children's Hospital of Philadelphia (CHOP) have determined what happens at a cellular level as the lung alveolus forms and allows newborns to breathe air. Understanding this process gives researchers a better ...
Mar 11, 2021
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It is well established that people with cystic fibrosis (CF) have two faulty copies of the CFTR gene, but debate continues on the question of whether certain symptoms of the airway disease are caused by the mutation or if ...
Jan 13, 2016
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Researchers across the globe continue their endeavors to improve our understanding of the mechanisms underlying COVID-19 infection and the pneumonia and lung damage occasionally associated with it. As part of these endeavors, ...
Jun 29, 2022
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