Alzheimer's disease & dementia

BACE-Inhibitor successfully tested in Alzheimer's animal model

The protein amyloid beta is believed to be the major cause of Alzheimer's disease. Substances that reduce the production of amyloid beta, such as BACE inhibitors, are therefore promising candidates for new drug treatments. ...

Alzheimer's disease & dementia

Blood test identifies key Alzheimer's marker

A new study led by researchers at Washington University School of Medicine in St. Louis suggests that measures of amyloid beta in the blood have the potential to help identify people with altered levels of amyloid in their ...

Neuroscience

Sleep, Alzheimer's link explained

A good night's sleep refreshes body and mind, but a poor night's sleep can do just the opposite. A study from Washington University School of Medicine in St. Louis, Radboud University Medical Centre in the Netherlands, and ...

Alzheimer's disease & dementia

Structural analysis of relevant drug targets for Alzheimer's disease

Alzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant. In AD, the beta-amyloid precursor protein (β-APP) that ...

Alzheimer's disease & dementia

Focus on Alzheimer's disease shifts to prevention

It has been 111 years since Auguste D. became the first person described with what is now called Alzheimer's disease. German psychiatrist Alois Alzheimer, for whom the disease is named, first publically reported his observations ...

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