An innovative laboratory culture system has succeeded, for the first time, in reproducing the full course of events underlying the development of Alzheimer's disease. Using the system they developed, investigators from the ...
Oct 12, 2014
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A hypothesis which has been the standard way of explaining how the body develops Alzheimer's Disease for almost 30 years is flawed, according to a University of Manchester biologist.
Oct 16, 2018
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Alzheimer's disease, a severely debilitating and ultimately fatal brain disorder, affects millions worldwide. To date, clinical efforts to find a cure or adequate treatment have met with dispiriting failure.
Jan 23, 2018
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For decades the amyloid hypothesis has dominated the research field in Alzheimer's disease. The theory describes how an increase in secreted beta-amyloid peptides leads to the formation of plaques, toxic clusters of damaged ...
Oct 28, 2011
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For researchers investigating Alzheimer's Disease (AD), a devastating neurodegenerative illness afflicting close to 6 million Americans, it is the best and worst of times.
Mar 18, 2020
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For decades, the field of Alzheimer's research has been dominated by a major hypothesis: that a build-up of beta amyloid (amyloid-β) in the brain causes Alzheimer's disease. However, despite years of research and billions ...
Oct 29, 2018
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Diseases that run in families usually have genetic causes. Some are genetic mutations that directly cause the disease if inherited. Others are risk genes that affect the body in a way that increases the chance someone will ...
Sep 15, 2023
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Last year, the FDA gave accelerated approval of the antibody aducanumab (marketed as Aduhelm by Biogen) for the treatment of Alzheimer's disease. The approval was based solely on a presumed reduction in the amount of the ...
Nov 16, 2022
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Despite a 99 percent failure rate and another major setback recently, Alzheimer's researchers are plowing ahead with hundreds of experiments - and a boost in federal money - to try to a crack a deadly disease that has flummoxed ...
Feb 10, 2017
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There is both risk and reward in focusing Alzheimer's disease research on inhibiting amyloid production, according to a new article in Future Science OA. The article reviews the significant body of research proposing that ...
Apr 20, 2015
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