Alzheimer's disease & dementia

Healthy mitochondria could stop Alzheimer's

Alzheimer's disease is the most common form of dementia and neurodegeneration worldwide. A major hallmark of the disease is the accumulation of toxic plaques in the brain, formed by the abnormal aggregation of a protein called ...

Alzheimer's disease & dementia

Brain tissue inflammation is key to Alzheimer's disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School ...

Alzheimer's disease & dementia

Scientists reveal how beta-amyloid may cause Alzheimer's

Scientists at the Stanford University School of Medicine have shown how a protein fragment known as beta-amyloid, strongly implicated in Alzheimer's disease, begins destroying synapses before it clumps into plaques that lead ...

Alzheimer's disease & dementia

Why BACE inhibitors may be failing Alzheimer's trials

Completely blocking the activity of an enzyme that produces amyloid plaques observed in Alzheimer's disease (AD) interferes with the regulation of new neurons generated in the adult hippocampus, according to a study of mice ...

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