Researchers at the University of Maryland School of Medicine (UMSOM) evaluated several human antibodies to determine the most potent combination to be mixed in a cocktail and used as a promising anti-viral therapy against ...
Jun 16, 2020
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A drug that is already clinically available for the treatment of nausea and psychosis, called prochlorperazine (PCZ), inhibits the internalization of receptors on the surface of tumor cells, thereby increasing the ability ...
Mar 05, 2020
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Most people living with HIV control the virus thanks to antiretroviral therapy (ART). Although this medication is highly effective, the presence of latent viral reservoirs in their bodies means they require lifelong therapy. ...
Feb 03, 2020
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A single dose of an antibody-based treatment can prevent HIV transmission from mother to baby, new nonhuman primate research suggests for the first time. The findings are being published in the journal Nature Communications.
Jan 07, 2020
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Antibody drug conjugates (ADCs)—cancer drugs that are designed to target and destroy cancerous tissue while leaving healthy cells intact—represent a long sought-after advancement in cancer therapy. ADCs work by attaching ...
Nov 08, 2019
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Immune checkpoint blockade (ICB) therapy using the antibody that combats the programmed cell death ligand 1 (PD-L1) shows great potential and is causing a revolution in clinical cancer management. Unfortunately, only a subset ...
Jul 12, 2019
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Medical Research Council scientists have isolated therapeutic antibodies from healthy volunteers exposed to the Ebola vaccine but not Ebola virus itself, suggesting that protective therapies could be developed from people ...
Apr 03, 2019
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Not so long ago, immunotherapy against cancer was positioned as an emerging or even promising treatment, but not one with a proven track record. Today however, novel immunotherapeutics across different tumor types, either ...
Oct 03, 2018
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With more than 35 million people worldwide living with the virus and nearly 2 million new cases each year, the human immunodeficiency virus (HIV) remains a major global epidemic. Existing antiretroviral drugs do not cure ...
Oct 03, 2018
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Thanks to improvements in antiretroviral therapy, HIV is now a manageable condition. Yet even the best drugs do not entirely eliminate the virus, which latently lingers in the body, threatening to rise to dangerous levels ...
Sep 26, 2018
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