Medical research

New study explains duality of longevity drug rapamycin

A Penn- and MIT-led team explained how rapamycin, a drug that extends mouse lifespan, also causes insulin resistance. The researchers showed in an animal model that they could, in principle, separate the effects, which depend ...

Diseases, Conditions, Syndromes

Better tests needed to identify Candida auris susceptibility

Matching an infection with Candida auris, a pathogenic yeast, to an effective antifungal is a critical clinical decision. That decision relies on susceptibility testing, but commercially available antifungal tests perform ...

Medications

New drug for vaginal yeast infections approved by FDA

(HealthDay)—A new and expensive antifungal drug to treat vaginal yeast infections was approved by the U.S. Food and Drug Administration this week, but critics say it is not needed.

Diseases, Conditions, Syndromes

New drug formulation could treat Candida infections

With antimicrobial resistance (AMR) increasing around the world, new research led by the University of Bristol has shown a new drug formulation could possibly be used in antifungal treatments against Candida infections.

Diseases, Conditions, Syndromes

Combination of drugs may combat deadly drug-resistant fungus

As health officials in New Jersey, Illinois and New York State scramble to contain the spread of a highly infectious and deadly fungus, microbiologists at Beth Israel Deaconess Medical Center (BIDMC) have shown that a combination ...

Diseases, Conditions, Syndromes

Off-patent drug appears promising as broad-spectrum antifungal

By screening a library of off-patent drugs, scientists have identified a compound with promising broad-spectrum antifungal activity. The compound, alexidine dihydrochloride, warrants further development as a pan-fungal, anti-biofilm ...

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