Medications

New hope for patients with relapsed large B-cell lymphoma

Of the 18,000 people diagnosed with large B-cell lymphoma each year, only half will be successfully treated with chemotherapy. The 9,000 remaining patients typically have poor outcomes, with only 25% responding to additional, ...

Immunology

Exhaustion affects CAR T–cell clinical response

St. Jude Children's Research Hospital is testing a treatment for cancer called a chimeric antigen receptor (CAR) T cell. T cells are a kind of immune cell. They help fight infections and diseases such as cancer. Scientists ...

Oncology & Cancer

Advancing treatment for B-cell acute lymphoblastic leukemia

A retrospective study led by Northwestern Medicine investigators found that the chimeric antigen receptor (CAR) T-cell immunotherapy drug tisagenlecleucel demonstrated safety and efficacy in pediatric patients with relapsed ...

Oncology & Cancer

A T-cell power-up for tumor treatments

Cancer is the second leading cause of death in the United States. But in recent years, a revolutionary therapy has brought new hope in the fight against the disease that takes the lives of nearly 600,000 Americans each year. ...

HIV & AIDS

Is it possible to deliver a knockout punch to HIV?

With a global focus on strategies to curb expansion of a fast-moving coronavirus pandemic, the question again has arisen: What more is being done about HIV, a scourge that has lasted more than 40 years—is a cure finally ...

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