A follow-up analysis of patients enrolled in a Phase I/II multi-center trial for diffuse large B-cell lymphoma (DLBCL) reported 51 percent of patients receiving an anti-CD19 chimeric antigen receptor (CAR T) called axi-cel ...
Dec 3, 2018
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In just a few years, CAR T-cell and other adoptive T-cell therapies have emerged as among the most promising forms of cancer immunotherapy. But even as these agents prove themselves against several forms of leukemia and lymphoma—and, ...
Oct 30, 2018
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In recent years, researchers have begun to fight cancer by genetically engineering a patient's own immune system to target the disease. Quad Technologies, a company that grew out of a Northeastern research lab, has been developing ...
Oct 18, 2018
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Fifteen years ago, Michael Jung was already an eminent scientist when his wife asked him a question that would change his career, and extend the lives of many men with a particularly lethal form of prostate cancer.
Mar 16, 2018
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Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical "antennas" on the surface of immune system T-cells. Their experiments with lab-grown ...
Jan 8, 2018
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Researchers at the Stanford University School of Medicine and their colleagues have developed a way to pinpoint potential targets for cancer therapies that rely on the body's immune system.
Dec 21, 2017
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New research by investigators at Brigham and Women's Hospital and Rockefeller University helps address a longstanding question about the inflammatory skin condition psoriasis: Why do skin lesions that have resolved with therapy ...
Sep 28, 2017
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Adoptive cell-therapies, in which a patient's own immune cells are used to recognize and target tumors, have shown breakthrough results for patients with certain B-cell malignancies, or cancers of the blood, but this therapy ...
Sep 14, 2016
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115
The efficacy of the immune system to combat disease makes the body's own healing powers a promising approach in the fight against cancer. A Berlin research group led by Wolfgang Uckert, Thomas Blankenstein and Matthias Leisegang ...
Feb 19, 2016
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Microbiologists at the University of British Columbia have uncovered a novel mechanism that boosts B-cells' sensitivity to extremely small amounts of foreign molecules.
Mar 12, 2015
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