Memory loss is often the first sign of Alzheimer's disease, followed by confusion and difficulty thinking. These symptoms reflect the typical pattern of worsening damage to brain tissues. Toxic clusters of proteins first ...
Nov 16, 2022
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Existing and emerging cancer drugs could be repurposed as therapies to be tested in clinical trials for people at genetic risk of Alzheimer's disease, according to a new study published in Science Advances. Research combining ...
Nov 10, 2021
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A well-known gene that increases Alzheimer's risk, called APOE4, has now been linked with better visual working memory in older adults, finds a new study led by University College London researchers.
Oct 7, 2021
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One of the most significant genetic risk factors for developing Alzheimer's disease is a gene called APOE4, which is carried by almost half of all Alzheimer's patients. A new study from MIT shows that this gene has widespread ...
Mar 3, 2021
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New USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system, allowing toxic substances to seep into the brain areas responsible for memory encoding and other ...
Apr 29, 2020
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People with a gene variant that puts them at high risk for Alzheimer's disease are protected from its debilitating effects if they also carry a variant of a completely different gene, Stanford University School of Medicine ...
Apr 13, 2020
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For a person with Alzheimer's disease, there's no turning back the clock. By the time she begins to experience memory loss and other worrisome signs, cognitive decline has already set in. And decades of clinical trials have ...
Nov 19, 2019
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An experimental drug known as A03, which was previously developed to treat depression, increases the levels of the enzyme Sirtuin1, or SirT1, and improves memory in mice. The mice were genetically modified to have a protein ...
Dec 21, 2018
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ApoE4, a protein linked to both Alzheimer's disease and a form of dementia caused by damage of blood vessels in the brain, increases the risk of cognitive impairment by reducing the number and responsiveness of blood vessels ...
Sep 20, 2018
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Greater aortic stiffness is related to lower cerebral blood flow, especially among individuals with increased genetic predisposition to Alzheimer's disease, according to research from Vanderbilt University Medical Center.
Aug 31, 2018
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