Autism spectrum disorders

Odds of autism up in children with congenital heart disease

(HealthDay)—The odds of developing autism spectrum disorder (AuSD) are increased for children with congenital heart disease (CHD), according to a study published online Oct. 10 in Pediatrics.

Autism spectrum disorders

Autism spectrum disorders linked with excess weight gain in children

A recent meta-analysis published in Obesity Reviews revealed that children with autism spectrum disorders had a 41.1% higher risk of developing obesity than matched groups of children, and on average, 22 out of 100 children ...

Autism spectrum disorders

Severe morning sickness associated with higher risk of autism

Children whose mothers had hyperemesis gravidarum—a severe form of a morning sickness—during pregnancy were 53% more likely to be diagnosed with autism spectrum disorder, according to Kaiser Permanente research published ...

Autism spectrum disorders

More U.S. kids being diagnosed with autism, ADHD

(HealthDay)—More U.S. children today have developmental disabilities like autism and ADHD than a decade ago, though improved recognition may be a major reason, according to a government study.

Oncology & Cancer

Predicting cancer versus autism risk in PTEN patients

In a new study published in American Journal of Human Genetics, a team of researchers led by Charis Eng, M.D., Ph.D., Chair of Cleveland Clinic's Genomic Medicine Institute, identified a metabolite that may predict whether ...

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Autism

Autism is a brain development disorder characterized by impaired social interaction and communication, and by restricted and repetitive behavior. These signs all begin before a child is three years old. Autism involves many parts of the brain; how this occurs is not well understood. The two other autism spectrum disorders (ASD) are Asperger syndrome, which lacks delays in cognitive development and language, and PDD-NOS, diagnosed when full criteria for the other two disorders are not met.

Autism has a strong genetic basis, although the genetics of autism are complex and it is unclear whether ASD is explained more by rare mutations, or by rare combinations of common genetic variants. In rare cases, autism is strongly associated with agents that cause birth defects. Controversies surround other proposed environmental causes, such as heavy metals, pesticides or childhood vaccines; the vaccine hypotheses are biologically implausible and lack convincing scientific evidence. The prevalence of ASD is about 6 per 1,000 people, with about four times as many males as females. The number of people known to have autism has increased dramatically since the 1980s, partly due to changes in diagnostic practice; the question of whether actual prevalence has increased is unresolved.

Parents usually notice signs in the first two years of their child's life. Although early behavioral or cognitive intervention can help children gain self-care, social, and communication skills, there is no known cure. Not many children with autism live independently after reaching adulthood, though some become successful. An autistic culture has developed, with some individuals seeking a cure and others believing autism should be tolerated as a difference and not treated as a disorder.

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