Medical research

Researchers use RNA to target pancreatic beta cells

Investigators at the University of Miami Miller School of Medicine have designed RNA molecules that home to human pancreatic beta cells, the cells that produce insulin and are destroyed in patients with type 1 and type 2 ...

Medical research

Cryo-EM imaging of STING protein reveals new binding pocket

Imaging at near-atomic resolution of a key immune protein commonly known as STING has revealed a previously unrecognized binding site that appears to be pivotal for launching immune attacks, UT Southwestern scientists report ...

Immunology

Getting under the skin of an autoimmune disorder

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed ...

Immunology

New way viruses trigger autoimmunity discovered

Autoimmune diseases such as rheumatoid arthritis and Type 1 diabetes are thought to arise when people with a genetic susceptibility to autoimmunity encounter something in the environment that triggers their immune systems ...

Immunology

Researchers uncover new subsets of CD4+ 'helper' T cells

T cells play important roles in helping to fight infections and cancers—and they can also drive autoimmune diseases. Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" ...

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