Researchers at the Institute of Molecular Biology (IMB) in Mainz, Germany, have made a breakthrough in understanding the origin of the ageing process. They have identified that genes belonging to a process called autophagy ...
Sep 15, 2017
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Columbia scientists have discovered that one of the body's natural defenses against amyotrophic lateral sclerosis (ALS)—a cellular 'clean-up process' called autophagy—suppresses disease progression early on, but in later ...
Sep 11, 2017
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Japanese biologist Yoshinori Ohsumi won the Nobel Prize in medicine on Monday for discoveries on how cells break down and recycle content, a garbage disposal system that scientists hope to harness in the fight against cancer, ...
Oct 3, 2016
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Melanoma is one of the types of cancer that poses the greatest challenge to researchers because it manifests in many ways, it contains a large number of mutations and displays high metastatic capacity. To date, clinicians ...
Sep 7, 2016
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Joslin researchers have uncovered the action of a gene that regulates the education of T cells, providing insight into how and why the immune system begins mistaking the body's own tissues for targets. The gene, Clec16a, ...
May 12, 2015
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The role of a phosphatase protein in promoting the self-destruction of healthy cells and the progression of ovarian cancer has been identified by A*STAR researchers. Known to be overexpressed in cancer cells, the protein, ...
Jan 21, 2015
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Scientists have discovered that Crohn's disease, the inflammatory bowel disorder, can originate from specialised intestinal cell type called Paneth cells. As such, they propose that small intestinal Crohn's disease might ...
Oct 2, 2013
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Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Wayne State University have discovered that tumor cell survival relies on adaptation to acidic conditions in the tumor microenvironment. ...
Sep 6, 2012
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The body has a built-in system known as autophagy, or 'self-eating,' that controls how cells live or die. Deregulation of autophagy is linked to the development of human diseases, including neural degeneration and cancer.
Aug 1, 2012
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