Genetics

It's not just what you eat, it's what's eating you

Restricting how much you eat without starving has been shown to robustly extend lifespan in more than 20 species of animals including primates. How this works is still unclear. In a new study published in PLOS Genetics, neuroscientists ...

Medical research

Scientists find rare disease clues in cell's recycling system

Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1). They found that a closely related compound will activate an enzyme, AMPK, triggering a cellular ...

Medical research

When a lack of sugar drives cells to eat themselves

Autophagy is the recycling process by which our cells keep themselves young. They continually break down and renew small parts of themselves in a kind of self-digestion; this helps to counteract harmful deposits which may ...

Medical research

Cells' garbage disposal may hold key to healthier life

Autophagy, the little-understood method by which human cells dispose of harmful waste and unwelcome intruders, may one day be central to therapies for longer, healthier living, experts said.

Medical research

Autophagy under the microscope as never before

We don't tend to wrap our recycling waste in bubble wrap but that's essentially what cells do during the cellular recycling process called autophagy. Using the live imaging capabilities at the Babraham Institute, Institute ...

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