It appears that autophagy protects neurons in the brain, but for different reasons than previously assumed, as researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and Charité in Berlin have ...
Nov 5, 2020
0
204
Autophagy, a key cellular auto-cleaning mechanism, mediates the formation of amyloid beta plaques, one of the hallmarks of Alzheimer's disease. It might be a potential drug target for the treatment of the disease, concludes ...
Oct 3, 2013
0
2
Did smokers do better than non-smokers in a clinical trial for an experimental cancer treatment? That was the intriguing question that led University of Iowa researchers and their colleagues to develop a drinkable, carbon ...
Jan 12, 2024
0
41
There are many indications that fasting promotes longevity. In recent years, much attention has been devoted to so-called caloric restriction mimetics (CMRs), substances that simulate the health-promoting effects of fasting ...
Oct 21, 2019
0
29
For the first time, the Max Planck Institute of Psychiatry and the University Hospital Bonn have been able to directly link a stress factor in the brain to the cell's recycling system and obesity. This could enable a completely ...
Mar 11, 2022
0
175
A University of Colorado Cancer Center study recently published in the journal Cell Reports and presented today at the American Association for Cancer Research (AACR) Annual Conference 2014 shows that the cellular process ...
Apr 5, 2014
0
0
Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center discovered a technique to make pancreatic cancer cells reliant on one energy source and then starve them of it—a finding that has led ...
Mar 4, 2019
0
53
Columbia scientists have discovered that one of the body's natural defenses against amyotrophic lateral sclerosis (ALS)—a cellular 'clean-up process' called autophagy—suppresses disease progression early on, but in later ...
Sep 11, 2017
1
135
A promising cancer treatment drug can restore function of a heart en route to failure from high blood pressure, researchers at UT Southwestern Medical Center have found.
May 31, 2011
0
0
Pancreatic ductal adenocarcinoma (PDAC) cells maintain a high level of autophagy or degradation, allowing them to thrive in severely limiting microenvironments. However, the process via which autophagy promotes pancreatic ...
