In a surprising study, Oregon State University researchers found that no matter how much stress they placed on mice from either a high-fat diet or strenuous exercise, the animals' mitochondria were able to adapt and continue ...
Feb 11, 2020
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UT Southwestern Medical Center researchers have identified a protein that is central to the immune system's ability to recognize and destroy the bacterium responsible for the global tuberculosis (TB) epidemic.The new finding, ...
Jan 12, 2017
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Dietary restriction, or limited food intake without malnutrition, has beneficial effects on longevity in many species, including humans. A new study from the Sanford Burnham Prebys Medical Discovery Institute (SBP), published ...
Jul 14, 2016
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What if we could treat obesity or type 2 diabetes by changing the way our cells take out the trash?
Aug 20, 2019
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Autophagy is an important biological recycling mechanism that is used to maintain homeostasis (balance or equilibrium) within all types of animal tissue. Many studies have attempted to understand the relationship between ...
Feb 20, 2019
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Coronary artery disease, the number one killer world-wide, restricts and ultimately blocks blood vessels, and cuts off oxygen supply to the heart. A study published on August 11 in the open access journal PLOS Biology reports ...
Aug 11, 2016
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Researchers from the University of Chicago have shown that inhibiting autophagy, a self-devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis ...
May 12, 2016
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Cells use various methods to break down and recycle worn-out components—autophagy is one of them. In the dissertation she will be defending at Umea University in Sweden, Karin Håberg shows that the protein SNX18 ...
Feb 27, 2012
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Researchers from the University of Queensland have identified that a gene associated with an increased risk of Parkinson's disease also contributes to a build-up of cell debris in the brain.
Feb 24, 2023
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Researchers at the RIKEN Brain Science Institute (BSI) have discovered a key mechanism responsible for selectively degrading aggregates of ubiquitinated proteins from the cell. Their findings indicate that the capture and ...
Nov 7, 2011
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